Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep846 | Reproductive and Developmental Endocrinology | ECE2020

Gonadal dysfunction is associated with severity of disease in men with myotonic dystrophy type 1

hoth guechot Hélène , Humbert Linda , Kohler Florence , Leroy Clara , Robin Geoffroy , Vantyghem Marie-Christine

Background: The myotonic dystrophy type 1 (DM1) or Steinert disease is the most common inherited, autosomal dominant neuromuscular disorder in adult. The gonadal dysfunction has been known for many years in DM1 men with description of bilateral testicular atrophy but the factors influencing the different profiles of gonadal dysfunction, and their natural evolution are not clearly established. The purpose of this study was to determine the profiles of gonadal function on men af...